I had a batch of Cottage cheese that would not solidify, but ended up draining them and using them for ricotta. Not a total loss.
With the milk that I have available to me, Grade A Pasteurized, I have to use CaCl2, and I still find that with the rennet, regardless of vegetable or animal, the setting times are considerably longer than advertised in the recipes. I made a Cheddar this weekend and used 2 gals whole milk, not ultra P, 1 tsp of CaCl2, 1/2 tsp of animal rennet, and 5 drop of vegetable rennet, 86% F constant temp and it took 6 hours to curd. I know milk has a lot to do with it, but the recipe indicated that it should have set in 45 minutes with just the animal rennet.
So many variables to deal with.